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ProtTech Inc. is dedicated to developing
innovative technologies and helping researchers to solve challenging problems
in life science research and drug discovery. We provide a range of services and
contract research to scientists from academic, biotechnology, and
pharmaceutical industries. Our mission is to help our customers to successfully
carry out R&D projects.
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Services for Life Science Research, Drug Discovery & Development
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Protein Identification Service
Identifying proteins
from SDS-PAGE gel bands, 2-D gel spots or protein solution samples. The
service is based on our ultra-sensitive Nano LC-MS/MS (tandem MS)
technology and we offer a high quality service with low-cost, rapid
turnover, conclusive results and guaranteed success. [Detail]
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Mapping of Protein Phosphorylation
Based on affinity enrichment and MS/MS phosphopeptide sequencing.
The service is capable of identifying the exact phosphorylated
Ser, Thr or Tyr residues from in vivo or in vitro phosphorylated
proteins. [Detail]
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Protein Biomarker Discovery
Identifying proteins that may be used as targets for therapeutic intervention or
for diagnostics of disease, or as indicators of drug treatment efficacy. By
applying our proprietary protein stable isotope labeling and separation
technologies, we are able to identify low-level target proteins from complex
mammalian cells or tissue samples. [Detail]
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Biopharmaceutical
Services
Providing
high quality analytical testing and characterization for biological
product development at relative low cost. The service offers the
most extensive package for protein characterization. In order to maximize
our support to customer’s need, these tests can be flexibly ordered
individually or as a package for Research Reference Standard release (COA),
comparability study, stability study, cell line development, purification
development, formulation development, and trouble shooting. [Detail]
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Mechanism of Action of Drug Candidates
Identifying protein targets that interact with drug molecules in
vivo. The information can be used in lead validation by determining
mechanism of action of the lead compound, as well as predicting the
potential toxicity arisen from undesired interaction with some important
cellular proteins. With our patented technology, low-level target
proteins can be confidently identified. [Detail]
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Metabolite
Identification
Identifying metabolites of drug candidate from human or animal in
vivo studies, or from in vitro incubation with liver hepatocytes or
microsomes of various species. By using our ultra-sensitive NanoLC-MS
platform with MSn capacity, we are able to provide detailed structural
information of low-level metabolites. [Detail]
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